Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue

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Authors

Victoria Keros · Karolinska University Hospital

Susanna Xella · University of Modena and Reggio Emilia

Kjell Hultenby · Karolinska University Hospital

Karin Pettersson · Karolinska University Hospital

Maryam Sheikhi · Karolinska University Hospital

Annibale Volpe · University of Modena and Reggio Emilia

Julius Hreinsson

Abstract

Vitrification using a combination of PrOH, EG, DMSO and PVP was comparable to slow freezing in terms of preserving follicles in human ovarian tissue. Ovarian stroma had significantly better morphological integrity after vitrification than after controlled-rate freezing.

Topics & Keywords

Reproductive Biology and Fertility Ovarian function and disorders Sperm and Testicular Function

Publication Details

Published in: Human Reproduction

Volume 24, Issue 7, pp. 1670-1683

DOI: 10.1093/humrep/dep079

Field-Weighted Citation Impact: 28.83

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Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue

Authors

Abstract

Topics & Keywords

Publication Details