Effect of Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis

2009493 citationsJournal Articlebronze Open Access

Authors

Heather Hsu · University of Pittsburgh

Kathleen A. Shutt · University of Pittsburgh

Matthew R. Moore · National Center for Immunization and Respiratory Diseases

Bernard Beall · National Center for Immunization and Respiratory Diseases

Nancy M. Bennett · University of Rochester

Allen S. Craig · Tennessee Department of Health

Monica M. Farley

Abstract

Rates of pneumococcal meningitis have decreased among children and adults since PCV7 was introduced. Although the overall effect of the vaccine remains substantial, a recent increase in meningitis caused by non-PCV7 serotypes, including strains nonsusceptible to antibiotics, is a concern.

Topics & Keywords

Pneumonia and Respiratory Infections Bacterial Infections and Vaccines Pneumocystis jirovecii pneumonia detection and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 360, Issue 3, pp. 244-256

DOI: 10.1056/nejmoa0800836

Field-Weighted Citation Impact: 35.21