FlyBase: enhancing Drosophila Gene Ontology annotations

2008708 citationsJournal Articlegold Open Access

Authors

Susan Tweedie · Harvard University

Michael Ashburner · University of Cambridge

Kathleen Falls · Harvard University

Paul Leyland · University of Cambridge

Peter McQuilton · Harvard University

Steven J Marygold · Harvard University

Gillian Millburn ·

Abstract

FlyBase (http://flybase.org) is a database of Drosophila genetic and genomic information. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. This article describes recent changes to the FlyBase GO annotation strategy that are improving the quality of the GO annotation data. Many of these changes stem from our participation in the GO Reference Genome Annotation Project--a multi-database collaboration producing comprehensive GO annotation sets for 12 diverse species.

Topics & Keywords

Genomics and Phylogenetic Studies Bioinformatics and Genomic Networks Biomedical Text Mining and Ontologies

Publication Details

Published in: Nucleic Acids Research

Volume 37, Issue Database, pp. D555-D559

DOI: 10.1093/nar/gkn788

Field-Weighted Citation Impact: 46.18

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FlyBase: enhancing Drosophila Gene Ontology annotations

Authors

Abstract

Topics & Keywords

Publication Details