Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

2014939 citationsJournal Articlebronze Open Access

Authors

Luis Villar · Industrial University of Santander

Gustavo H. Dayan · Sanofi (Mexico)

José Luis Arredondo-Garcı́a · Instituto Nacional de Pediatria

Doris Maribel Rivera

Rivaldo Venâncio da Cunha

Carmen Deseda

Humberto Reynales

Maria Selma Neves da Costa · Universidade Federal de Goiás

Javier O Morales-Ramirez

Abstract

The CYD-TDV dengue vaccine was efficacious against VCD and severe VCD and led to fewer hospitalizations for VCD in five Latin American countries where dengue is endemic. (Funded by Sanofi Pasteur; ClinicalTrials.gov number, NCT01374516.).

Topics & Keywords

Mosquito-borne diseases and control Malaria Research and Control Viral Infections and Vectors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 372, Issue 2, pp. 113-123

DOI: 10.1056/nejmoa1411037

Field-Weighted Citation Impact: 129.89