Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems

200774 citationsJournal Article

Authors

Gildas Réthoré · Institut des Sciences Chimiques de Rennes

Tristan Montier · Inserm

Tony Le Gall · Université de Bretagne Occidentale

Pascal Delépine · Établissement Français du Sang

Sandrine Cammas‐Marion · École Nationale Supérieure de Chimie de Rennes

Loı̈c Lemiègre · École Nationale Supérieure de Chimie de Rennes

P Lehn

Abstract

Novel cationic liposomes, termed "archaeosomes", based on mixtures of neutral/cationic bilayer-forming lipids and archaeobacterial synthetic tetraether-type bipolar lipids show efficient in vitro gene transfection properties and represent a new approach for modulating the lipidic membrane fluidity of the complexes they form with DNA.

Topics & Keywords

RNA Interference and Gene Delivery Advanced biosensing and bioanalysis techniques Nanopore and Nanochannel Transport Studies

Publication Details

Published in: Chemical Communications

DOI: 10.1039/b618568a

Field-Weighted Citation Impact: 1.57

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Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems

Authors

Abstract

Topics & Keywords

Publication Details