Regulation of an Enzyme Cascade Reaction by a DNA Machine

2013161 citationsJournal Article

Authors

Chao Zhou · National Center for Nanoscience and Technology

Abstract

A strategy for the regulation of enzyme cascade reaction efficiency by a DNA machine in vitro is presented. Two cascade enzymes (GOx and HRP) are attached to the DNA machine, and the enzyme cascade reaction shows much higher efficiency when the two enzymes are brought closer by the DNA machine than when they are distant.

Topics & Keywords

Advanced biosensing and bioanalysis techniques DNA and Nucleic Acid Chemistry RNA Interference and Gene Delivery

Publication Details

Published in: Small

Volume 9, Issue 18, pp. 3088-3091

DOI: 10.1002/smll.201300019

Field-Weighted Citation Impact: 5.41

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Regulation of an Enzyme Cascade Reaction by a DNA Machine

Authors

Abstract

Topics & Keywords

Publication Details