Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture.

19941,105 citationsJournal Articlebronze Open Access

Authors

Pedro Moreno · Massachusetts General Hospital

Erling Falk · Massachusetts General Hospital

Igor F. Palacios · Massachusetts General Hospital

John Newell · Massachusetts General Hospital

Valentı́n Fuster · Massachusetts General Hospital

John T. Fallon · Massachusetts General Hospital

Abstract

Macrophage-rich areas are more frequently found in patients with unstable angina and non-Q-wave myocardial infarction. This suggests that macrophages are a marker of unstable atherosclerotic plaques and may play a significant role in the pathophysiology of acute coronary syndromes.

Topics & Keywords

Coronary Interventions and Diagnostics Atherosclerosis and Cardiovascular Diseases Cardiac Imaging and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 90, Issue 2, pp. 775-778

DOI: 10.1161/01.cir.90.2.775

Field-Weighted Citation Impact: 35.63