Chemotherapy of Advanced Hodgkin's Disease with MOPP, ABVD, or MOPP Alternating with ABVD

19921,152 citationsJournal Articlebronze Open Access

Authors

George P. Canellos · Dana-Farber Cancer Institute

James R. Anderson · Dana-Farber Cancer Institute

Kathleen J. Propert · Dana-Farber Cancer Institute

Nis I. Nissen · Dana-Farber Cancer Institute

M. Robert Cooper · Dana-Farber Cancer Institute

Edward S. Henderson · Dana-Farber Cancer Institute

Mark R. Green

Abstract

In this trial, ABVD therapy for 6 to 8 months was as effective as 12 months of MOPP alternating with ABVD, and both were superior to MOPP alone in the treatment of advanced Hodgkin's disease. ABVD was less myelotoxic than MOPP or ABVD alternating with MOPP.

Topics & Keywords

Lymphoma Diagnosis and Treatment CNS Lymphoma Diagnosis and Treatment Lung Cancer Treatments and Mutations

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 327, Issue 21, pp. 1478-1484

DOI: 10.1056/nejm199211193272102

Field-Weighted Citation Impact: 21.24