MiR-21 Indicates Poor Prognosis in Tongue Squamous Cell Carcinomas as an Apoptosis Inhibitor

2009430 citationsJournal Article

Authors

Jinsong Li · National Medical Research Center of Dentistry and Maxillofacial Surgery

Hongzhang Huang · National Medical Research Center of Dentistry and Maxillofacial Surgery

Lijuan Sun

Mei Yang

Chaobin Pan · National Medical Research Center of Dentistry and Maxillofacial Surgery

Wei‐Liang Chen · National Medical Research Center of Dentistry and Maxillofacial Surgery

Donghui Wu · National Medical Research Center of Dentistry and Maxillofacial Surgery

Abstract

miR-21 is an independent prognostic indicator for TSCC, and may play a role in TSCC development by inhibiting cancer cell apoptosis partly via TPM1 silencing.

Topics & Keywords

MicroRNA in disease regulation Cancer-related molecular mechanisms research RNA modifications and cancer

UN Sustainable Development Goals

No povertyGood health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 15, Issue 12, pp. 3998-4008

DOI: 10.1158/1078-0432.ccr-08-3053

Field-Weighted Citation Impact: 13.71