Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

2008936 citationsJournal Articlebronze Open Access

Authors

Valeriya Lyssenko · Lund University

Anna Jonsson · Lund University

Peter Almgren · Lund University

Nicolò Pulizzi · University of Pisa

Bo Isomaa · Folkhälsans Forskningscentrum

Tiinamaija Tuomi · University of Helsinki

Göran Berglund · Lund University

Abstract

As compared with clinical risk factors alone, common genetic variants associated with the risk of diabetes had a small effect on the ability to predict the future development of type 2 diabetes. The value of genetic factors increased with an increasing duration of follow-up.

Topics & Keywords

Genetic Associations and Epidemiology Metabolism, Diabetes, and Cancer Epigenetics and DNA Methylation

Publication Details

Published in: New England Journal of Medicine

Volume 359, Issue 21, pp. 2220-2232

DOI: 10.1056/nejmoa0801869

Field-Weighted Citation Impact: 54.90

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Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

Authors

Abstract

Topics & Keywords

Publication Details