Validation of a Radiosensitivity Molecular Signature in Breast Cancer

2012208 citationsJournal Articlegreen Open Access

Authors

Steven A. Eschrich · Moffitt Cancer Center

William J. Fulp · Cancer Research And Biostatistics

Yudi Pawitan · Sophiahemmet Hospital

John A. Foekens · Sophiahemmet Hospital

Marcel Smid · Sophiahemmet Hospital

John W.M. Martens · Sophiahemmet Hospital

Michelle Echevarria ·

Abstract

RSI is validated in 2 independent breast cancer datasets totaling 503 patients. Including prior data, RSI is validated in 5 independent cohorts (621 patients) and represents, to our knowledge, the most extensively validated molecular signature in radiation oncology.

Topics & Keywords

Radiopharmaceutical Chemistry and Applications Breast Cancer Treatment Studies Computational Drug Discovery Methods

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 18, Issue 18, pp. 5134-5143

DOI: 10.1158/1078-0432.ccr-12-0891

Field-Weighted Citation Impact: 8.02