The distribution and gender difference of CYP3A activity in Chinese subjects

200378 citationsJournal Articlebronze Open Access

Authors

Bing Zhu · PharmacoGenetics (China)

Zhaoqian Liu · PharmacoGenetics (China)

Guo‐Lin Chen · PharmacoGenetics (China)

Xiaoping Chen · Central South University

Dongsheng Ouyang · PharmacoGenetics (China)

Liansheng Wang · Central South University

Song‐Lin Huang ·

Abstract

A normal distribution of CYP3A activity was observed in the Chinese population. The CYP3A activity is higher in female subjects than in males. CYP3A activity differed across the phases of the menstrual cycle.

Topics & Keywords

Pharmacogenetics and Drug Metabolism Drug Transport and Resistance Mechanisms Pharmacological Effects and Toxicity Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Clinical Pharmacology

Volume 55, Issue 3, pp. 264-269

DOI: 10.1046/j.1365-2125.2003.01728.x

Field-Weighted Citation Impact: 5.21