Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene

200267 citationsJournal Articlebronze Open Access

Authors

Masashi Ikeno · Fujita Health University

Hidehito Inagaki · Fujita Health University

Keiko Nagata · Japan Science and Technology Agency

Miwa Morita · Japan Science and Technology Agency

Hiroshi Ichinose · Fujita Health University

Tuneko Okazaki · Japan Science and Technology Agency

Abstract

These HACs will provide a useful system for analysis of the complex regulatory circuit of the GCH1 gene in vivo and also function as a tool for gene delivery in animal models or in therapeutic trials.

Topics & Keywords

CRISPR and Genetic Engineering Metabolism and Genetic Disorders Pluripotent Stem Cells Research

Publication Details

Published in: Genes to Cells

Volume 7, Issue 10, pp. 1021-1032

DOI: 10.1046/j.1365-2443.2002.00580.x

Field-Weighted Citation Impact: 2.34

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Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene

Authors

Abstract

Topics & Keywords

Publication Details