Acute Histologic Chorioamnionitis at Term: Nearly Always Noninfectious

2012154 citationsJournal Articlegold Open Access

Authors

Drucilla J. Roberts · Massachusetts General Hospital

Ann C. Celi · Harvard University

Laura E. Riley · Harvard University

Andrew B. Onderdonk · Brigham and Women's Hospital

Theonia K. Boyd · Harvard University

Lise C. Johnson · Brigham and Women's Hospital

Ellice Lieberman ·

Abstract

Our results suggest histologic chorioamnionitis at term most often results from a noninfectious inflammatory process. It was strongly associated with fever, most of which was related to epidural used for pain relief. A more 'activated' maternal immune system at admission was also associated with histologic chorioamnionitis.

Topics & Keywords

Preterm Birth and Chorioamnionitis Neonatal Respiratory Health Research Reproductive tract infections research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 7, Issue 3, pp. e31819-e31819

DOI: 10.1371/journal.pone.0031819

Field-Weighted Citation Impact: 6.97