In Vivo Imaging of Endogenous Pancreatic β-Cell Mass in Healthy and Type 1 Diabetic Subjects Using <sup>18</sup>F-Fluoropropyl-Dihydrotetrabenazine and PET

2012114 citationsJournal Articlebronze Open Access

Authors

Marc D. Normandin · Yale University

Kitt Falk Petersen · Yale University

Yu‐Shin Ding · Yale University

Shu-fei Lin · Yale University

Sarita Naik · Yale University

Krista Fowles · Yale University

Daniel Skovronsky

Kevan C. Herold

Abstract

These findings demonstrate that quantitative evaluation of islet β-cell density and aggregate BCM can be performed clinically with (18)F-FP-(+)-DTBZ PET.

Topics & Keywords

Pancreatic function and diabetes Diabetes and associated disorders Diabetes Management and Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Nuclear Medicine

Volume 53, Issue 6, pp. 908-916

DOI: 10.2967/jnumed.111.100545

Field-Weighted Citation Impact: 11.16