Increased mortality among patients taking digoxin--analysis from the AFFIRM study

2012279 citationsJournal Articlebronze Open Access

Authors

Matthew G. Whitbeck · University of Kentucky

Richard Charnigo · University of Kentucky

Paul Khairy · University of Kentucky

Khaled M. Ziada · University of Kentucky

Alison Bailey · University of Kentucky

Milagros Zegarra · University of Kentucky

Jignesh Shah ·

Abstract

Digoxin was associated with a significant increase in all-cause mortality in patients with AF after correcting for clinical characteristics and comorbidities, regardless of gender or of the presence or absence of HF. These findings call into question the widespread use of digoxin in patients with AF.

Topics & Keywords

Atrial Fibrillation Management and Outcomes Cardiac electrophysiology and arrhythmias Heart Failure Treatment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Heart Journal

Volume 34, Issue 20, pp. 1481-1488

DOI: 10.1093/eurheartj/ehs348

Field-Weighted Citation Impact: 19.54