Randomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer

2014188 citationsJournal Articlebronze Open Access

Authors

Mitesh J. Borad · Louisiana State University Health Sciences Center Shreveport

Shantan Reddy · Louisiana State University Health Sciences Center Shreveport

Nathan Bahary · Louisiana State University Health Sciences Center Shreveport

Hope E. Uronis · Louisiana State University Health Sciences Center Shreveport

Darren Sigal · Louisiana State University Health Sciences Center Shreveport

Allen Lee Cohn · Louisiana State University Health Sciences Center Shreveport

Abstract

PFS, tumor response, and CA 19-9 response were significantly improved with G+TH-302. G+T340 is being investigated further in the phase III MAESTRO study (NCT01746979).

Topics & Keywords

Pancreatic and Hepatic Oncology Research Cancer, Hypoxia, and Metabolism Neuroblastoma Research and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 33, Issue 13, pp. 1475-1481

DOI: 10.1200/jco.2014.55.7504

Field-Weighted Citation Impact: 11.20