Outcomes for COPD pharmacological trials: from lung function to biomarkers

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Authors

Mario Cazzola · University of Rome Tor Vergata

William MacNee · University of Rome Tor Vergata

Fernando J. Martínez · University of Rome Tor Vergata

Klaus F. Rabe · University of Rome Tor Vergata

Luigi G. Franciosi · University of Rome Tor Vergata

Peter J. Barnes · University of Rome Tor Vergata

Vito Brusasco

Abstract

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

Topics & Keywords

Chronic Obstructive Pulmonary Disease (COPD) Research Asthma and respiratory diseases Respiratory Support and Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Respiratory Journal

Volume 31, Issue 2, pp. 416-469

DOI: 10.1183/09031936.00099306

Field-Weighted Citation Impact: 53.84