Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4-hydroxylase (CYP53)

201388 citationsJournal Article

Authors

Branka Korošec · National Institute of Chemistry

Matej Sova · University of Ljubljana

Samo Turk · University of Ljubljana

Nada Kraševec · National Institute of Chemistry

Metka Novak · National Institute of Chemistry

Ljerka Lah · National Institute of Chemistry

Jure Stojan ·

Abstract

By identifying selected derivatives of cinnamic acid as possible antifungal drugs, and CYP53 family enzymes as their targets, we revealed a potential inhibitor-target system for antifungal drug development.

Topics & Keywords

Insect Pest Control Strategies Biochemical and biochemical processes Essential Oils and Antimicrobial Activity

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Applied Microbiology

Volume 116, Issue 4, pp. 955-966

DOI: 10.1111/jam.12417

Field-Weighted Citation Impact: 5.00