KPNA2 Expression Is an Independent Adverse Predictor of Biochemical Recurrence after Radical Prostatectomy

201197 citationsJournal Articlebronze Open Access

Authors

Ashkan Mortezavi · University of Bern

Thomas Hermanns · University of Regensburg

Hans‐Helge Seifert · University of Regensburg

Martin Baumgartner · Universitätsklinikum Erlangen

Maurizio Provenzano · University of Regensburg

Tullio Sulser · University of Bern

Maximilian Burger ·

Abstract

KPNA2 is a novel independent prognostic marker for disease progression after radical prostatectomy. This allows to identify patients who need more aggressive treatment. It can moreover be speculated that patients not suited for surveillance regimens might be identified at initial biopsy by a positive KPNA2 immunohistochemistry.

Topics & Keywords

Nuclear Structure and Function RNA Research and Splicing Genomics and Chromatin Dynamics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 17, Issue 5, pp. 1111-1121

DOI: 10.1158/1078-0432.ccr-10-0081

Field-Weighted Citation Impact: 4.69