Parallel Evolution of <i>Bacillus thuringiensis</i> Toxin Resistance in Lepidoptera

2011277 citationsJournal Articlebronze Open Access

Authors

Simon W. Baxter · University of Cambridge

Francisco Rubén Badenes‐Pérez · Instituto de Ciencias Agrarias

Anna Morrison · University of Cambridge

Heiko Vogel · Max Planck Institute for Chemical Ecology

Neil Crickmore · University of Sussex

Wendy Kain · New York State Department of Agriculture and Markets

Ping Wang

Abstract

Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.

Topics & Keywords

Insect Resistance and Genetics Genetically Modified Organisms Research Insect Pest Control Strategies

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Genetics

Volume 189, Issue 2, pp. 675-679

DOI: 10.1534/genetics.111.130971

Field-Weighted Citation Impact: 8.01