<i>STAT4</i> and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus

20071,042 citationsJournal Articlebronze Open Access

Authors

Elaine F. Remmers · National Institute of Arthritis and Musculoskeletal and Skin Diseases

Robert M. Plenge · Broad Institute

Annette T. Lee · Feinstein Institute for Medical Research

Robert Graham · Broad Institute

Geoffrey Hom

Timothy W. Behrens

Paul I. W. de Bakker · Broad Institute

Julie Le

Abstract

A haplotype of STAT4 is associated with increased risk for both rheumatoid arthritis and systemic lupus erythematosus, suggesting a shared pathway for these illnesses.

Topics & Keywords

Chronic Lymphocytic Leukemia Research Immunodeficiency and Autoimmune Disorders Monoclonal and Polyclonal Antibodies Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 357, Issue 10, pp. 977-986

DOI: 10.1056/nejmoa073003

Field-Weighted Citation Impact: 60.67