Persistent Low‐Level Viremia in HIV‐1 Elite Controllers and Relationship to Immunologic Parameters

2009198 citationsJournal Articlebronze Open Access

Authors

Florencia Pereyra · Brigham and Women's Hospital

Sarah Palmer · Karolinska Institutet

Toshiyuki Miura · Ragon Institute of MGH, MIT and Harvard

Brian L. Block · Ragon Institute of MGH, MIT and Harvard

Ann Wiegand · National Institutes of Health

Alissa C. Rothchild · Ragon Institute of MGH, MIT and Harvard

B.M. Baker

Abstract

Low-level viremia is present in the majority of elite controllers and is associated with higher HIV-1-specific antibody responses. Absolute CD4(+) T cell loss is more common among viremic individuals, suggesting that even very low-level viremia has negative consequences over time.

Topics & Keywords

HIV Research and Treatment HIV/AIDS Research and Interventions HIV/AIDS drug development and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 200, Issue 6, pp. 984-990

DOI: 10.1086/605446

Field-Weighted Citation Impact: 7.56