Valsartan, Captopril, or Both in Myocardial Infarction Complicated by Heart Failure, Left Ventricular Dysfunction, or Both

20032,480 citationsJournal Articlebronze Open Access

Authors

Marc A. Pfeffer · Brigham and Women's Hospital

John J.V. McMurray

Eric J. Velazquez · Duke Medical Center

Jean‐Lucien Rouleau · Montreal Heart Institute

Lars Køber · Rigshospitalet

Aldo P. Maggioni · Associazione Nazionale Medici Cardiologi Ospedalieri

Scott D. Solomon · Brigham and Women's Hospital

Abstract

Valsartan is as effective as captopril in patients who are at high risk for cardiovascular events after myocardial infarction. Combining valsartan with captopril increased the rate of adverse events without improving survival.

Topics & Keywords

Heart Failure Treatment and Management Potassium and Related Disorders Cardiovascular Function and Risk Factors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 349, Issue 20, pp. 1893-1906

DOI: 10.1056/nejmoa032292

Field-Weighted Citation Impact: 108.03