DNA methylation arrays as surrogate measures of cell mixture distribution

20123,420 citationsJournal Articlegold Open Access

Authors

E. Andrés Houseman · Oregon State University

William P. Accomando · Brown University

Devin C. Koestler · Dartmouth College

Brock C. Christensen · Dartmouth College

Carmen J. Marsit · Dartmouth College

Heather H. Nelson · University of Minnesota

John K. Wiencke ·

Abstract

Our method, in combination with an appropriate external validation set, promises new opportunities for large-scale immunological studies of both disease states and noxious exposures.

Topics & Keywords

Epigenetics and DNA Methylation Single-cell and spatial transcriptomics Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Bioinformatics

Volume 13, Issue 1, pp. 86-86

DOI: 10.1186/1471-2105-13-86

Field-Weighted Citation Impact: 46.40