Important Role of Nox4 Type NADPH Oxidase in Angiogenic Responses in Human Microvascular Endothelial Cells In Vitro

2007177 citationsJournal Articlebronze Open Access

Authors

Srinivasa Raju Datla · O'Brien Institute

Hitesh Peshavariya · O'Brien Institute

Gregory J. Dusting · O'Brien Institute

Kalyankar Mahadev · O'Brien Institute

Barry J. Goldstein · O'Brien Institute

Fan Jiang · O'Brien Institute

Abstract

Nox4 type NADPH oxidase promotes endothelial angiogenic responses, at least partly, via enhanced activation of receptor tyrosine kinases and the downstream Erk pathway.

Topics & Keywords

Neutrophil, Myeloperoxidase and Oxidative Mechanisms Nitric Oxide and Endothelin Effects Cell Adhesion Molecules Research

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 27, Issue 11, pp. 2319-2324

DOI: 10.1161/atvbaha.107.149450

Field-Weighted Citation Impact: 3.65

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Important Role of Nox4 Type NADPH Oxidase in Angiogenic Responses in Human Microvascular Endothelial Cells In Vitro

Authors

Abstract

Topics & Keywords

Publication Details