Incomplete Inhibition of Thromboxane Biosynthesis by Acetylsalicylic Acid

2008228 citationsJournal Article

Authors

John W. Eikelboom · Inserm

Graeme J. Hankey · Inserm

Jim Thom · Inserm

Deepak L. Bhatt · Inserm

Philippe Gabríel Steg · Inserm

Gilles Montalescot · Inserm

S. Claiborne Johnston · Inserm

Abstract

In aspirin-treated patients, urinary concentrations of 11-dehydro thromboxane B(2) are an externally valid and potentially modifiable determinant of stroke, myocardial infarction, or cardiovascular death in patients at risk for atherothrombotic events.

Topics & Keywords

Antiplatelet Therapy and Cardiovascular Diseases Inflammatory mediators and NSAID effects Lipoproteins and Cardiovascular Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 118, Issue 17, pp. 1705-1712

DOI: 10.1161/circulationaha.108.768283

Field-Weighted Citation Impact: 11.10