Circulating Tumor Cells: A Novel Prognostic Factor for Newly Diagnosed Metastatic Breast Cancer

20051,131 citationsJournal Articlebronze Open Access

Authors

Massimo Cristofanilli · The University of Texas MD Anderson Cancer Center

Daniel F. Hayes · Washington University in St. Louis

G. Thomas Budd · Cleveland Clinic

Mathew J. Ellis · Michigan Center for Translational Pathology

Alison Stopeck · Washington University in St. Louis

James M. Reuben · Washington University in St. Louis

Gerald V. Doyle

Abstract

Detection of CTCs before initiation of first-line therapy in patients with MBC is highly predictive of PFS and OS. This technology can aid in appropriate patient stratification and design of tailored treatments.

Topics & Keywords

Cancer Cells and Metastasis Cancer Genomics and Diagnostics Metastasis and carcinoma case studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 23, Issue 7, pp. 1420-1430

DOI: 10.1200/jco.2005.08.140

Field-Weighted Citation Impact: 19.57