Cognitive/personality pattern and triplet expansion size in adult myotonic dystrophy type 1 (DM1): CTG repeats, cognition and personality in DM1

2009101 citationsJournal Article

Authors

Andone Sistiaga · Biogipuzkoa Health Research Institute

Iratxe Urreta · Biogipuzkoa Health Research Institute

Mercé Jódar · Universitat Autònoma de Barcelona

A.M. Cobo · Association Francaise contre les Myopathies

José Ignacio Emparanza · Biogipuzkoa Health Research Institute

David Otaegui · Biogipuzkoa Health Research Institute

J J Poza

Abstract

Besides muscular symptomatology, there is significant CTG-dependent involvement of the CNS in adult DM1 patients. Our data indicate that the cognitive impairment predominantly affects the fronto-parietal lobe.

Topics & Keywords

Genetic Neurodegenerative Diseases Parkinson's Disease Mechanisms and Treatments Mitochondrial Function and Pathology

Publication Details

Published in: Psychological Medicine

Volume 40, Issue 3, pp. 487-495

DOI: 10.1017/s0033291709990602

Field-Weighted Citation Impact: 1.93

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Cognitive/personality pattern and triplet expansion size in adult myotonic dystrophy type 1 (DM1): CTG repeats, cognition and personality in DM1

Authors

Abstract

Topics & Keywords

Publication Details