Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping

2013109 citationsJournal Articlegold Open Access

Authors

Hye-Ryoun Kim

Sung Yong Lee · Korea University Medical Center

Dae-Sung Hyun · Daegu Catholic University Medical Center

Min Ki Lee · Pusan National University Hospital

Hyun-Kyung Lee · Inje University Busan Paik Hospital

Chang‐Min Choi · Asan Medical Center

Sei-Hoon Yang · Wonkwang University

Abstract

The detection rate of EGFR mutations from plasma was not so high despite highly sensitive EGFR mutation test suggesting that more advances in detection methods and further exploration of characteristics of circulating free DNA are required.

Topics & Keywords

Lung Cancer Treatments and Mutations Cancer Genomics and Diagnostics Cholangiocarcinoma and Gallbladder Cancer Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 32, Issue 1, pp. 50-50

DOI: 10.1186/1756-9966-32-50

Field-Weighted Citation Impact: 9.48