Preliminary study on the effect of parenteral naloxone, alone and in association with calcium gluconate, on bone healing in an ovine "drill hole" model system

200721 citationsJournal Articlegold Open Access

Authors

Lucio Petrizzi · University of Teramo

Massimo Mariscoli · University of Teramo

Luca Valbonetti · University of Teramo

Vincenzo Varasano · University of Teramo

Jens D Langhoff · Institute of Musculoskeletal Science & Education (United States)

Brigitte von Rechenberg · University of Zurich

Abstract

A low-dose parenteral regimen of naloxone enhances mineralization and remodelling of the callus in healing cortical defects in sheep, especially if associated with calcium gluconate.

Topics & Keywords

Anesthesia and Pain Management Spine and Intervertebral Disc Pathology Inflammatory mediators and NSAID effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Musculoskeletal Disorders

Volume 8, Issue 1, pp. 43-43

DOI: 10.1186/1471-2474-8-43

Field-Weighted Citation Impact: 1.17