Nrf2 Overexpression Predicts Prognosis and 5-FU Resistance in Gastric Cancer

201382 citationsJournal Articlegold Open Access

Authors

Xiufeng Hu · First Affiliated Hospital of Henan University of Science and Technology

Jun Yao

Abstract

Our data show that Nrf2 is an independent prognostic factor in GC. Furthermore, Nrf2 confers resistance to chemotherapeutic drug 5-FU in GC cells. Taken together, Nrf2 is a potential prognostic marker and predictive for 5-FU resistance in GC.

Topics & Keywords

Genomics, phytochemicals, and oxidative stress Family Support in Illness Endometriosis Research and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Asian Pacific Journal of Cancer Prevention

Volume 14, Issue 9, pp. 5231-5235

DOI: 10.7314/apjcp.2013.14.9.5231

Field-Weighted Citation Impact: 3.07