Compassionate Use of Bedaquiline for the Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: Interim Analysis of a French Cohort

2014186 citationsJournal Articlebronze Open Access

Authors

Lorenzo Guglielmetti · Sorbonne Université

D. Le Dû · AlterSanté

M. Jachym · AlterSanté

Benoît Henry · Hospital for Tropical Diseases

D. Martin · Centre d'Immunologie et des Maladies Infectieuses

Éric Caumes · Hospital for Tropical Diseases

Nicolas Véziris ·

Abstract

The use of bedaquiline combined with other active drugs has the potential to achieve high culture conversion rates in complicated MDR and XDR tuberculosis cases, with a reassuring safety profile at 6 months of treatment.

Topics & Keywords

Tuberculosis Research and Epidemiology Mycobacterium research and diagnosis Pneumocystis jirovecii pneumonia detection and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 60, Issue 2, pp. 188-194

DOI: 10.1093/cid/ciu786

Field-Weighted Citation Impact: 13.84