A naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblasts

201259 citationsJournal Articlebronze Open Access

Authors

Gaurav Swarnkar · Central Drug Research Institute

Kunal Sharan · Central Drug Research Institute

Jawed A. Siddiqui · Central Drug Research Institute

J. S. Mishra · Central Drug Research Institute

Kainat Khan · Central Drug Research Institute

Mohd Parvez Khan · Central Drug Research Institute

Varsha Gupta

Abstract

NCG is a potent derivative of naringenin that has bone anabolic action through the activation of osteoblast ERs and exhibited substantial oral bioavailability.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Pharmacology

Volume 165, Issue 5, pp. 1526-1542

DOI: 10.1111/j.1476-5381.2011.01637.x

Field-Weighted Citation Impact: 3.92