TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

19897,585 citationsReview

Authors

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Topics & Keywords

Immune Cell Function and Interaction T-cell and B-cell Immunology Monoclonal and Polyclonal Antibodies Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annual Review of Immunology

Volume 7, Issue 1, pp. 145-173

DOI: 10.1146/annurev.iy.07.040189.001045

Field-Weighted Citation Impact: 52.19