Prolonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigen

2015127 citationsJournal Article

Authors

Tianying Zhang · Xiamen University

Quan Yuan · Xiamen University

Jinghua Zhao · Xiamen University

Yali Zhang · Xiamen Blood Center

Lunzhi Yuan · Xiamen University

Ying Lan · Xiamen University

Yu‐Chieh Lo · Institute of Biomedical Sciences, Academia Sinica

Abstract

These results provided new insight into understanding the therapeutic role and mechanism of antibody against persistent viral infection. The E6F6-like mAbs may provide a novel immunotherapeutic agent against human chronic HBV infection.

Topics & Keywords

Hepatitis B Virus Studies Hepatitis C virus research Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gut

Volume 65, Issue 4, pp. 658-671

DOI: 10.1136/gutjnl-2014-308964

Field-Weighted Citation Impact: 7.84