The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition

201590 citationsJournal Articlehybrid Open Access

Authors

Loyse Hippolyte · University of Lausanne

Anne Maillard · University of Lausanne

Borja Rodríguez‐Herreros · University of Lausanne

Aurélie Pain · University of Lausanne

Sandra Martin-Brevet · University of Lausanne

Carina Ferrari · University of Lausanne

Philippe Conus ·

Abstract

The simultaneous study of reciprocal CNVs suggests that the 16p11.2 genomic locus modulates specific cognitive skills according to the number of genomic copies. Further research is warranted to replicate these findings and elucidate the molecular mechanisms modulating these cognitive performances.

Topics & Keywords

Genomic variations and chromosomal abnormalities Congenital heart defects research Autism Spectrum Disorder Research

UN Sustainable Development Goals

Quality Education

Publication Details

Published in: Biological Psychiatry

Volume 80, Issue 2, pp. 129-139

DOI: 10.1016/j.biopsych.2015.10.021

Field-Weighted Citation Impact: 7.16