Follicle-Stimulating Hormone Induces Postmenopausal Dyslipidemia Through Inhibiting Hepatic Cholesterol Metabolism

2015119 citationsJournal Articlebronze Open Access

Authors

Yang Song · Women's Hospital, School of Medicine, Zhejiang University

En-Sheng Wang · Women's Hospital, School of Medicine, Zhejiang University

Lili Xing · Women's Hospital, School of Medicine, Zhejiang University

Shuai Shi · Zhejiang University

Fan Qu · Ministry of Education of the People's Republic of China

Dan Zhang · Ministry of Education of the People's Republic of China

Abstract

FSH may interact with its receptors in hepatocytes and reduce LDLR levels, which subsequently attenuates the endocytosis of LDL-C, resulting in an elevated circulating LDL-C level.

Topics & Keywords

Phytoestrogen effects and research Cancer, Lipids, and Metabolism Liver Disease Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 101, Issue 1, pp. 254-263

DOI: 10.1210/jc.2015-2724

Field-Weighted Citation Impact: 3.99