Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer

201562 citationsJournal Articlehybrid Open Access

Authors

Aram S. A. van Brussel · Utrecht University

Arthur L.L. Adams · University Medical Center Utrecht

Sabrina Oliveira · University Medical Center Utrecht

Bram Dorresteijn · Utrecht University

Mohamed El Khattabi · Qserve Group (Netherlands)

Jeroen F. Vermeulen · University Medical Center Utrecht

Elsken van der Wall

Abstract

These results demonstrate the successful generation of a CAIX-specific nanobody-IRDye800CW conjugate that can be used for rapid imaging of (pre-)invasive breast cancer.

Topics & Keywords

Nanoplatforms for cancer theranostics Cancer, Hypoxia, and Metabolism Photodynamic Therapy Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Imaging and Biology

Volume 18, Issue 4, pp. 535-544

DOI: 10.1007/s11307-015-0909-6

Field-Weighted Citation Impact: 2.91