Physiological Levels of Melatonin Relate to Cognitive Function and Depressive Symptoms: The HEIJO-KYO Cohort

201545 citationsJournal Articlebronze Open Access

Authors

Kenji Obayashi

Keigo Saeki

Junko Iwamoto · Tenri Health Care University

Nobuhiro Tone

Kunihiko Tanaka · Osaka City University

Hiroshi Kataoka · Nara City Hospital

Masayuki Morikawa · Nara Medical University

Norio Kurumatani

Abstract

Significant associations of higher physiological melatonin levels with lower prevalence of cognitive impairment and depressed mood were revealed in a large general elderly population. The association between physiological melatonin levels and cognitive function was independent of depressive symptoms.

Topics & Keywords

Circadian rhythm and melatonin Sleep and related disorders Health, Environment, Cognitive Aging

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 100, Issue 8, pp. 3090-3096

DOI: 10.1210/jc.2015-1859

Field-Weighted Citation Impact: 2.26