Differential Opioid Tolerance and Opioid-induced Hyperalgesia

2015233 citationsReview

Authors

Christina J. Hayhurst · Vanderbilt University

Marcel E. Durieux · Vanderbilt University

Abstract

Abstract Differential opioid tolerance (different degrees and speed of tolerance to various opioid side effects) and opioid-induced hyperalgesia (increased pain with escalating doses of opioids) potentially complicate the postoperative management.

Topics & Keywords

Anesthesia and Pain Management Pain Management and Opioid Use Pain Mechanisms and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesiology

Volume 124, Issue 2, pp. 483-488

DOI: 10.1097/aln.0000000000000963

Field-Weighted Citation Impact: 10.36