Randomized Trial of Low-Dose Morphine Versus Weak Opioids in Moderate Cancer Pain

2015181 citationsJournal Articlebronze Open Access

Authors

Elena Bandieri · GlaxoSmithKline (Netherlands)

Marilena Romero · Otsuka (Germany)

Carla Ripamonti · GlaxoSmithKline (Netherlands)

Fabrizio Artioli · GlaxoSmithKline (Netherlands)

Daniela Sichetti · Astellas Pharma (United Kingdom)

Caterina Fanizza · Bristol-Myers Squibb (Germany)

Daniele Santini

Abstract

In patients with cancer and moderate pain, low-dose morphine reduced pain intensity significantly compared with weak opioids, with a similarly good tolerability and an earlier effect.

Topics & Keywords

Pain Management and Opioid Use Pharmacological Effects and Toxicity Studies Pediatric Pain Management Techniques

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 34, Issue 5, pp. 436-442

DOI: 10.1200/jco.2015.61.0733

Field-Weighted Citation Impact: 17.45