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Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

2015442 citationsJournal Articlebronze Open Access

Authors

Kensuke Tateishi · Massachusetts General Hospital

Hiroaki Wakimoto · Harvard University

A. John Iafrate · Harvard University

Shota Tanaka · Massachusetts General Hospital

Franziska Loebel · Massachusetts General Hospital

Nina Lelic · Harvard University

Dmitri Wiederschain ·

Topics & Keywords

Glioma Diagnosis and Treatment Cancer, Hypoxia, and Metabolism Epigenetics and DNA Methylation

UN Sustainable Development Goals

Affordable and clean energy

Publication Details

Published in: Cancer Cell

Volume 28, Issue 6, pp. 773-784

DOI: 10.1016/j.ccell.2015.11.006

Field-Weighted Citation Impact: 17.65

Sanofi (United States)

Olivier Bedel · Sanofi (United States)

Gejing Deng · Sanofi (United States)

Bailin Zhang · Sanofi (United States)

Timothy He · Sanofi (United States)

Xu Shi · Harvard University

Robert E. Gerszten · Harvard University

Yiyun Zhang · Harvard University

Jing-Ruey Joanna Yeh · Harvard University

William T. Curry · Massachusetts General Hospital

Dan Zhao · Harvard University

Sudhandra Sundaram · Massachusetts General Hospital

Fares Nigim · Harvard University

Mara V.A. Koerner · Harvard University

Quan Ho · Massachusetts General Hospital

David E. Fisher · Harvard University

Elisabeth Roider · Harvard University

Lajos V. Kemény · Harvard University

Yardena Samuels · Weizmann Institute of Science

Keith T. Flaherty · Harvard University

Tracy T. Batchelor · Massachusetts General Hospital

S. Andrew · Massachusetts General Hospital

Daniel P. Cahill · Harvard University

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion | Researchclopedia