Dietary Iron Oxide Nanoparticles Delay Aging and Ameliorate Neurodegeneration in <i>Drosophila</i>

2015219 citationsJournal Article

Authors

Yi Zhang · Shanghai Institute of Applied Physics

Zhu-Yao Wang · China National Center for Food Safety Risk Assessment

Xiaojiao Li · China National Center for Food Safety Risk Assessment

Lu Wang · Shanghai Institute of Applied Physics

Min Yin · Shanghai Institute of Applied Physics

Lihua Wang · Shanghai Institute of Applied Physics

Nan Chen

Abstract

Dietary iron oxide nanoparticles are shown to ameliorate neurodegeneration in a Drosophelia Alzheimer's disease model. Iron oxide nanoparticles can mimic catalase and can decompose reactive oxygen species (ROS). This has potential therapeutic uses for aging, metabolic disorders, and neurodegenerative diseases, in which increased production of ROS is closely implicated.

Topics & Keywords

Alzheimer's disease research and treatments Trace Elements in Health Nanoparticles: synthesis and applications

Publication Details

Published in: Advanced Materials

Volume 28, Issue 7, pp. 1387-1393

DOI: 10.1002/adma.201503893

Field-Weighted Citation Impact: 8.67

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Dietary Iron Oxide Nanoparticles Delay Aging and Ameliorate Neurodegeneration in <i>Drosophila</i>

Authors

Abstract

Topics & Keywords

Publication Details