ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

Research should include both fundamental and clinical investigation defining pathogenesis of increased vascular and LV stiffness; RCTs to define appropriate treatment thresholds and goals; comparative effectiveness trials testing various treatment strategies (ie, different regimens and different intensities of lifestyle modification); and assessing the relative safety and efficacy of these approaches in the prevention of mortality and morbidity.