<i>Fusobacterium nucleatum</i>in colorectal carcinoma tissue and patient prognosis

20151,035 citationsJournal Articlegreen Open Access

Authors

Kosuke Mima · Harvard University

Reiko Nishihara · Harvard University

Zhi Rong Qian · Dana-Farber Cancer Institute

Yin Cao · Harvard University

Yasutaka Sukawa · Dana-Farber Cancer Institute

Jonathan A. Nowak · Harvard University

Juhong Yang ·

Abstract

The amount of F. nucleatum DNA in colorectal cancer tissue is associated with shorter survival, and may potentially serve as a prognostic biomarker. Our data may have implications in developing cancer prevention and treatment strategies through targeting GI microflora by diet, probiotics and antibiotics.

Topics & Keywords

Colorectal Cancer Screening and Detection Diverticular Disease and Complications Gut microbiota and health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gut

Volume 65, Issue 12, pp. 1973-1980

DOI: 10.1136/gutjnl-2015-310101

Field-Weighted Citation Impact: 21.55