Highly Multiplexed Profiling of Low Abundance Tumor Mutations in Plasma.

20131 citationsJournal Article

Authors

Matthew Wiggin

Joel Pel

Valentina Vysotskaia · Collège Boréal

David Broemeling

Andre Marziali · University of British Columbia

Dan Hanson

Abstract

We have demonstrated a novel somatic mutation enrichment methodology demonstrating multiplexed detection of tumor mutations in plasma with sensitivity as low as 0.01% compared to normal DNA.

Topics & Keywords

Cancer Genomics and Diagnostics CRISPR and Genetic Engineering Genetics, Bioinformatics, and Biomedical Research

Publication Details

Published in: Europe PMC (PubMed Central)

Volume 24

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Highly Multiplexed Profiling of Low Abundance Tumor Mutations in Plasma.

Authors

Abstract

Topics & Keywords

Publication Details