Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea

2016543 citationsJournal Articlebronze Open Access

Authors

Johan van Griensven · Instituut voor Tropische Geneeskunde

Tansy Edwards · London School of Hygiene & Tropical Medicine

Xavier de Lamballerie · École des Hautes Études en Santé Publique

Malcolm G. Semple · University of Liverpool

Pierre Gallian · Aix-Marseille Université

Sylvain Baize · Institut Pasteur

Peter Horby

Abstract

The transfusion of up to 500 ml of convalescent plasma with unknown levels of neutralizing antibodies in 84 patients with confirmed EVD was not associated with a significant improvement in survival. (Funded by the European Union's Horizon 2020 Research and Innovation Program and others; ClinicalTrials.gov number, NCT02342171.).

Topics & Keywords

Viral Infections and Outbreaks Research Disaster Response and Management Hepatitis B Virus Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 374, Issue 1, pp. 33-42

DOI: 10.1056/nejmoa1511812

Field-Weighted Citation Impact: 32.14