Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis

201652 citationsJournal Articlegold Open Access

Authors

Nathella Pavan Kumar · International Centers for Excellence in Research

Vaithilingam V. Banurekha · International Centers for Excellence in Research

Dina Nair · National Institute of Research in Tuberculosis

Subash Babu · International Centers for Excellence in Research

Abstract

Therefore, our data demonstrate that PTB is associated with elevated levels of circulating angiogenic factors, possibly reflecting vascular and endothelial dysfunction. In addition, some of these circulating angiogenic factors could prove useful as biomarkers to monitor disease severity, bacterial burden and therapeutic responses.

Topics & Keywords

Lymphatic System and Diseases Inflammation biomarkers and pathways Venous Thromboembolism Diagnosis and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 11, Issue 1, pp. e0146318-e0146318

DOI: 10.1371/journal.pone.0146318

Field-Weighted Citation Impact: 2.49