Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods

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Authors

Tamás Baranyai · Semmelweis University

Kata Herczeg · Semmelweis University

Zsófia Onódi · Semmelweis University

István Voszka · Semmelweis University

Károly Módos · Semmelweis University

Nikolett Marton · Semmelweis University

György Nagy ·

Abstract

Here we show that it is feasible to isolate exosomes from blood plasma by SEC without significant albumin contamination albeit with low vesicle yield.

Topics & Keywords

Extracellular vesicles in disease RNA Interference and Gene Delivery

Publication Details

Published in: PLoS ONE

Volume 10, Issue 12, pp. e0145686-e0145686

DOI: 10.1371/journal.pone.0145686

Field-Weighted Citation Impact: 18.83

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Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods

Authors

Abstract

Topics & Keywords

Publication Details